Conditioned Medium Reconditions Hippocampal Neurons against Kainic Acid Induced Excitotoxicity: AnIn VitroStudy
نویسندگان
چکیده
منابع مشابه
Conditioned Medium Reconditions Hippocampal Neurons against Kainic Acid Induced Excitotoxicity: An In Vitro Study
Stem cell therapy is gaining attention as a promising treatment option for neurodegenerative diseases. The functional efficacy of grafted cells is a matter of debate and the recent consensus is that the cellular and functional recoveries might be due to "by-stander" effects of grafted cells. In the present study, we investigated the neuroprotective effect of conditioned medium (CM) derived from...
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The effects of kainic acid (KA) on neurogenesis in the developing rat hippocampus were investigated. Neonatal [postnatal day (P) 7] rats received a single bilateral intracerebroventricular infusion of KA (50 nmol in 1.0 microl) or vehicle. At P14, P25, P40, and P60, the spatial and temporal relationships between the neurodegeneration and neurogenesis induced by KA were explored using terminal d...
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ژورنال
عنوان ژورنال: Journal of Toxicology
سال: 2014
ISSN: 1687-8191,1687-8205
DOI: 10.1155/2014/194967